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Penpulimab

CAT: 0804-HY-P99108-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P99108-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Penpulimab is an IgG1 backbone anti-PD-1 monoclonal antibody with antitumor activities[1].
CAS Number
2350298-92-7
Product Name Alternative
AK-105
UNSPSC
12352203
Target
PD-1/PD-L1
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/penpulimab.html
Purity
98.80
Solubility
H2O
Smiles
[Penpulimab]
Molecular Weight
(145.14 kDa)
References & Citations
[1]Huang Z, et al. Penpulimab, an Fc-Engineered IgG1 Anti-PD-1 Antibody, With Improved Efficacy and Low Incidence of Immune-Related Adverse Events. Front Immunol. 2022 Jun 27;13:924542.|[2]Yunlong Shan, et al. Anlotinib enhanced penpulimab efficacy through remodeling of tumor vascular architecture and immune microenvironment in hPD-L1/hPD-1 humanized mouse model. Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021) 2581-2581.
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched

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