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CELF2 Antibody / CUGBP2 / ETR3

CAT: 0800-V9365-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V9365-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL)
UniProt
O95319
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human CELF2/CUGBP2 protein was used as the immunogen for the CELF2 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
PCRP-CELF2-1E4
Applications
FACS, IF
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the CELF2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CELF2 antibody is available for research use only.
Storage Conditions
Aliquot the CELF2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the CELF2 antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Immunofluorescent staining of PFA-fixed human HeLa cells using CELF2 antibody (green) and phalloidin (red) .

UniProtKB · O95319

CUGBP Elav-like family member 2

CELF2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95319
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CELF2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CELF-2
EC number
—
Processing
—
Secondary accessions
B7ZAN9, Q7KYU4, Q8N499, Q92950, Q96NW9, Q96RQ5, Q96RQ6, Q9UL67
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Disease

Disease variantEpilepsyIntellectual disability

Biological process

mRNA processing

Domain

Repeat

Molecular function

RepressorRNA-binding

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MBS6411238-01CELF2 (CUGBP, Elav-like Family Member 2, ETR3, ETR-3, NAPOR, CUGBP2, BRUNOL3) (PE)

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