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JUNB Antibody

CAT: 0800-V9262SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#: V9262SAF-100UGSize: 100 µg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE) . Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL
UniProt
P17275
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human JUNB protein was used as the immunogen for the JUNB antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
PCRP-JUNB-3G2
Applications
FACS, IF
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the JUNB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This JUNB antibody is available for research use only.
Storage Conditions
Aliquot the JUNB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the JUNB antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Immunofluorescent staining of PFA-human HeLa cells using JUNB antibody (green, clone PCRP-JUNB-3G2) and phalloidin (red) .

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