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Daxx Antibody

CAT: 0800-V9187-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V9187-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Daxx interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, it functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL
UniProt
Q9UER7
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human DAXX protein was used as the immunogen for the Daxx antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
PCRP-DAXX-8B7
Applications
FACS, IF
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Daxx antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Daxx antibody is available for research use only.
Storage Conditions
Aliquot the Daxx antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Daxx antibody should be determined by the researcher.
Location
Nucleus, Cytoplasm
Image Legend
Analysis of HuProt (TM) microarray containing more than 19,000 full-length human proteins using Daxx antibody (clone PCRP-DAXX-8B7) . These results demonstrate the foremost specificity of the PCRP-DAXX-8B7 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

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