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Moesin Antibody

CAT: 0800-V9046-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V9046-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes 78kDa moesin protein. Moesin, a member of the Talin-4.1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Western blot: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL
UniProt
P26038
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for this Moesin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SPM562
Applications
IHC-P, WB, IF
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Moesin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Moesin antibody is available for research use only.
Storage Conditions
Store the Moesin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cell surface
Image Legend
IHC: Formalin-fixed, paraffin-embedded human placenta stained with Moesin antibody (clone SPM562) .

UniProtKB · P26038

Moesin

MOES_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P26038
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MSN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinS-nitrosylation

Cellular component

Cell membraneCell projectionCytoplasmCytoskeletonMembrane

Disease

Disease variant

Biological process

Host-virus interaction

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