Products for Research Use Only

Fibronectin Antibody

CAT: 0800-V9021SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V9021SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This mAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this mAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating mAb indicating that it can be used to specifically target tumor vessels in vivo.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P02751
Host
Mouse
Reactivity
Human
Immunogen
A T-lymphoma biopsy was used as the immunogen for this Fibronectin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SPM246
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the Fibronectin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Fibronectin antibody is available for research use only.
Storage Conditions
Store the Fibronectin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
The optimal dilution of the Fibronectin antibody for each application should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9 for 10-20 min followed by cooling at RT for 20 minutes.
Location
Connective tissue matrix
Image Legend
IHC: Formalin-fixed, paraffin-embedded human pancreatic adenocarcinoma stained with Fibronectin antibody (SPM246) .

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