(S,R,S)-Me-AHPC-amide-C3-alkyne

(S,R,S)-Me-AHPC-amide-C3-alkyne

• CAS Number: 3016512-69-6
• UNSPSC Description: (S,R,S)-Me-AHPC-amide-C3-alkyne is an E3 ligase ligand-linker conjugate used for the synthesis of JWZ-5-13 (HY-161828)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-me-ahpc-amide-c3-alkyne.html
• Smiles: C#CCCCC(N[C@@H](C(C)(C)C)C(N1C[C@H](O)C[C@H]1C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O
• Molecular Weight: 538.70
• References & Citations: [1]Ji W, et al. Discovery of Bivalent Small Molecule Degraders of Cyclin-dependent Kinase 7 (CDK7)[J]. European Journal of Medicinal Chemistry, 2024: 116613.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported