Products for Research Use Only
RegisterLogin

CD63 Antibody / LAMP-3

CAT: 0800-V8875-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V8875-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
CAS Number
9007-83-4
Specifications
ELISA: 1-5 µg/mL (order BSA-free format for coating), Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P08962
Host
Mouse
Reactivity
Human
Immunogen
Full-length human CD63 protein was used as the immunogen for the CD63 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
LAMP3/4949
Applications
ELISA, FACS, IF, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the CD63 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD63 antibody is available for research use only.
Storage Conditions
Aliquot the CD63 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the CD63 antibody should be determined by the researcher.
Location
Cell surface, Cytoplasm
Image Legend
FACS staining of bead-bound exosomes derived from MCF-7 cells: Unstained exosomes (gray) and exosomes stained with CD63 antibody (orange, clone LAMP3/4949) .

UniProtKB · P08962

CD63 antigen

CD63_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08962
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD63
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
F8VZE2, Q5TZP3, Q8N6Z9, Q9UCG6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndosomeLysosomeMembraneSecreted

PTM

GlycoproteinLipoproteinPalmitate

Biological process

Protein transportTransport

Domain

TransmembraneTransmembrane helix

Related Products

CatalogName
V3028-100UGLAMP-3 Antibody / CD63
V3029SAF-100UGLAMP-3 Antibody / CD63
V3029-100UGLAMP-3 Antibody / CD63
V3028-20UGLAMP-3 Antibody / CD63
V3028SAF-100UGLAMP-3 Antibody / CD63
V3029IHC-7MLLAMP-3 Antibody / CD63
V3029-20UGLAMP-3 Antibody / CD63
V5450SAF-100UGRecombinant LAMP-3 Antibody / CD63
V4299-100UGRecombinant LAMP-3 Antibody / CD63
V5450-100UGRecombinant LAMP-3 Antibody / CD63

Alternative Products

CatalogName
GTR18575078CD63 Antibody / LAMP-3
GTR18572937LAMP-3 Antibody / CD63

Popular Products