Interferon alpha 1 Antibody / IFNA1
CAT:
800-V8790-100UG
Size:
100 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Interferon alpha 1 Antibody / IFNA1
- Description: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.Produced by macrophages, IFN-alphas have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase
- CAS Number: 9007-83-4
- UniProt: P01562
- Host: Mouse
- Immunogen: Recombinant human IFNA1 protein was used as the immunogen for the Interferon alpha 1 antibody.
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Applications: WB, IHC-P
- Format: Purified
- Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
- Reconstitution: Aliquot the Interferon alpha 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This Interferon alpha 1 antibody is available for research use only.