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Beta Amyloid Antibody

CAT: 0800-V8732-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8732-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the /A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P05067
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 578-680 from the human protein was used as the immunogen for the Beta Amyloid antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
APP/3343
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Beta Amyloid antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Beta Amyloid antibody is available for research use only.
Storage Conditions
Store the Beta Amyloid antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Beta Amyloid antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human brain with Beta Amyloid antibody (clone APP/3343) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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