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Adiponectin Antibody

CAT: 0800-V8692-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8692-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore, adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. Clone ADPN/4256 is used to detect plasma adiponectin concentrations.
CAS Number
9007-83-4
Specifications
ELISA: order BSA-free format for coating*, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q15848
Host
Mouse
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the tail region of the Adiponectin molecule was used as the immunogen for the Adiponectin antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
ADPN/4256
Applications
ELISA, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Adiponectin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Adiponectin antibody is available for research use only.
Storage Conditions
Store the Adiponectin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
ADPN/4255
Location
Cytoplasmic & Cell surface
Image Legend
IHC staining of FFPE human kidney with Adiponectin antibody (clone ADPN/4256) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

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