Adiponectin Antibody

CAT: 0800-V8691-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V8691-100UGSize:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore, adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. (Hotta K, et al.)
CAS Number
9007-83-4
Specifications
ELISA: order BSA-free format for coating*, Western blot: 1-2 µg/mL
UniProt
Q15848
Host
Mouse
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the globular head region of the Adiponectin molecule was used as the immunogen for the Adiponectin antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
ADPN/4255
Applications
ELISA, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Adiponectin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Adiponectin antibody is available for research use only.
Storage Conditions
Store the Adiponectin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
ADPN/4256
Location
Cytoplasm and Cell surface
Image Legend
Western blot testing of human kidney lysate with Adiponectin antibody. Predicted molecular weigth ~30 kDa.

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