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HSP90AB1 Antibody

CAT: 0800-V8606-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V8606-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P08238
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 581-704 from the human protein was used as the immunogen for the HSP90AB1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
HSP90AB1/3952
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the HSP90AB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This HSP90AB1 antibody is available for research use only.
Storage Conditions
Store the HSP90AB1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the HSP90AB1 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Analysis of HuProt (TM) microarray containing more than 19,000 full-length human proteins using HSP90AB1 antibody. These results demonstrate the foremost specificity of the HSP90AB1/3952 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

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