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Integrin alpha V + beta 6 Antibody

CAT: 0800-V8494-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V8494-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
CAS Number
9007-83-4
Specifications
Immunoprecipitation: 1-2ug/500ug protein, Flow cytometry: 0.5-1ug/million cells, Immunofluorescence: 1-2 µg/mL, Western blot: 0.5-1 µg/mL
UniProt
P06756; P18564
Host
Rat
Reactivity
Human
Immunogen
Mouse fibroblasts retrovirally infected with cDNA to express a mouse/human avb6 chimera was used as the immunogen for the Integrin alpha V + beta 6 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
AvB6 53a.2
Applications
IP, FACS, IF, WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Integrin alpha V + beta 6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Integrin alpha V + beta 6 antibody is available for research use only.
Storage Conditions
Store the Integrin alpha V + beta 6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Integrin alpha V + beta 6 antibody should be determined by the researcher.
Location
Membrane
Image Legend
SDS-PAGE analysis of purified, BSA-free Integrin alpha V + beta 6 antibody (clone AvB6 53a.2) as confirmation of integrity and purity.

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