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C-Myc Antibody

CAT: 0800-V8454-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V8454-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.
CAS Number
9007-83-4
Specifications
ELISA: order Ab without BSA for coating
UniProt
P01106
Host
Mouse
Reactivity
Human
Immunogen
Amino acids AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA from C-terminus of the human protein was used as the immunogen for the c-Myc antibody. The epitope has been mapped to amino acids EQKLISEEDL.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
9E11.
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the c-Myc antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This c-Myc antibody is available for research use only.
Storage Conditions
Store the c-Myc antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the c-Myc antibody should be determined by the researcher.
Location
Nuclear
Image Legend
SDS-PAGE analysis of purified, BSA-free c-Myc antibody as confirmation of integrity and purity.
Product Datasheet
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