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INHA Antibody

CAT: 0800-V8391-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8391-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
It recognizes a 47kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH) . Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P05111
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 233-264, corresponding to the N-terminus of the mature region of the human inhibin alpha subunit, were used as the immunogen for the INHA antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
R1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the INHA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This INHA antibody is available for research use only.
Storage Conditions
Store the INHA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the INHA antibody should be determined by the researcher.
Location
Cytoplasmic (secreted) and Nuclear
Image Legend
IHC staining of FFPE human testicular carcinoma with INHA antibody (clone R1) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

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