BCL10 Antibody

• Description:

  BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t (1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14 translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

• Specifications:

  Flow cytometry: 1-2ug/million cells, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

• UniProt:

  O95999

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Amino acids 122-168 from the human protein were used as the immunogen for the BCL10 antibody.

• Clonality:

  Recombinant Monoclonal

• Isotype:

  IgG1 k

• Clone:

  RBL10/411

• Type:

  Recombinant

• Applications:

  FACS, IHC-P

• Purity:

  Protein G affinity chromatography

• Format:

  Purified

• Buffer:

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Reconstitution:

  Store the BCL10 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This BCL10 antibody is available for research use only.

• Storage Conditions:

  Store the BCL10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation:

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

• Applications Notes:

  Optimal dilution of the BCL10 antibody should be determined by the researcher.

• CAS Number:

  9000-83-3

• Location:

  Nuclear and cytoplasmic

• Image Legend:

  Flow cytometry testing of PFA-fixed human K562 cells with BCL10 antibody (clone rBL10/411) ; Red=isotype control, Blue= BCL10 antibody.