Bcl10 Antibody

• Description :

  BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t (1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

• Specifications :

  Immunohistochemistry (FFPE) : 1-2 µg/mL

• UniProt :

  O95999

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  A recombinant human partial protein (amino acids 122-168) was used as the immunogen for this Bcl10 antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG1 k

• Clone :

  151

• Applications :

  IHC-P

• Purity :

  Protein G affinity chromatography

• Format :

  Purified

• Buffer :

  0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Reconstitution :

  Store the Bcl10 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations :

  This Bcl10 antibody is available for research use only.

• Storage Conditions :

  Store the Bcl10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation :

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

• Applications Notes :

  Optimal dilution of the Bcl10 antibody should be determined by the researcher.

• CAS Number :

  9007-83-4

• Location :

  Nuclear, cytoplasmic

• Image Legend :

  IHC staining of FFPE human tonsil with Bcl10 antibody (clone 151) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.