C1QA Antibody / Complement C1q A-Chain

CAT: 0800-V8133SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V8133SAF-100UGSize:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P02745
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 104-237 were used as the immunogen for the C1QA antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
CCSA-1
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the C1QA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This C1QA antibody is available for research use only.
Storage Conditions
Store the C1QA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
The stated application concentrations are suggested starting points. Titration of the C1QA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Secreted
Image Legend
Western blot testing of human PC3 cell lysate with C1QA antibody (clone CCSA-1) . Predicted molecular weight ~26 kDa.

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