C1QA Antibody / Complement C1q A-Chain

• Description:

  C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. [UniProt]

• Specifications:

  Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL

• UniProt:

  P02745

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Amino acids 104-237 were used as the immunogen for the C1QA antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG2b κ

• Clone:

  CCSA-1

• Applications:

  WB, IHC-P

• Purity:

  Protein G affinity chromatography

• Format:

  Purified

• Buffer:

  0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Reconstitution:

  Store the C1QA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This C1QA antibody is available for research use only.

• Storage Conditions:

  Store the C1QA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation:

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

• Applications Notes:

  The stated application concentrations are suggested starting points. Titration of the C1QA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Location:

  Secreted

• Image Legend:

  Western blot testing of human PC3 cell lysate with C1QA antibody (clone CCSA-1) . Predicted molecular weight ~26 kDa.