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P73 Antibody

CAT: 0800-V8089-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V8089-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
O15350
Host
Mouse
Reactivity
Human
Immunogen
A recombinant full-length human protein was used as the immunogen for this p73 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
P73/2531
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the p73 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This p73 antibody is available for research use only.
Storage Conditions
Store the p73 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the p73 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC staining of FFPE human skin with p73 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Product Datasheet
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