PD-L1 Antibody / B7-H1 / CD274

• Description:

  PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

• Specifications:

  ELISA (order BSA-free format for coating)

• UniProt:

  Q9NZQ7

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 39-191 from the human protein was used as the immunogen for this PD-L1 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 k

• Clone:

  PDL1/2745

• Applications:

  ELISA

• Purity:

  Protein G affinity chromatography

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Store the PD-L1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This PD-L1 antibody is available for research use only.

• Storage Conditions:

  Store the PD-L1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation:

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• Applications Notes:

  Optimal dilution of the PD-L1 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Location:

  Cell surface, cytoplasmic