Myelin Basic Protein (TFA)

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CAT:

804-HY-P1821A-01

Size:

10 mg

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Myelin Basic Protein (TFA)

UNSPSC Description: Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein TFA is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts[1][2].
Target Antigen: PKC
Type: Peptides
Related Pathways: Epigenetics;TGF-beta/Smad
Applications: Neuroscience-Neuromodulation
Field of Research: Neurological Disease
Assay Protocol: https://www.medchemexpress.com/myelin-basic-protein-tfa.html
Purity: 97.35
Solubility: H2O : ≥ 100 mg/mL
Smiles: O=C(O)C(F)(F)F.O=C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(N)=O)N
Molecular Weight: 1504.61
References & Citations: [1]Farrar YJ, et al. A phosphatase resistant substrate for the assay of protein kinase C in crude tissue extracts. Biochem Biophys Res Commun. 1991;180(2):694-701. |[2]Yasuda I, et al. A synthetic peptide substrate for selective assay of protein kinase C. Biochem Biophys Res Commun. 1990;166(3):1220-1227.Heliyon. 2024 Oct 30;10(21):e39933.|Autophagy. 2020 Oct;16(10):1823-1837.
Shipping Conditions: Blue Ice
Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Clinical Information: No Development Reported

Complementary Product Range

Our range of products, including Myelin Basic Protein (TFA), falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

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