TUBB3 Antibody / Beta Tubulin

• Description:

  This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3.In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation.

• Specifications:

  Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 1-2 µg/mL

• UniProt:

  Q13509

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Amino acids 437-450 were used as the immunogen for the TUBB3 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 k

• Clone:

  TUBB3/3731

• Applications:

  IHC-P, WB

• Purity:

  Protein G affinity chromatography

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Store the TUBB3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This TUBB3 antibody is available for research use only.

• Storage Conditions:

  Store the TUBB3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation:

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• Applications Notes:

  Optimal dilution of the TUBB3 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Location:

  Cytoplasmic

• Image Legend:

  IHC staining of FFPE human brain with TUBB3 antibody (TUBB3/3731) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.