SOX2 Recombinant Antibody

SOX2 Recombinant Antibody

• Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. [UniProt]
• CAS Number: 9000-83-3
• UniProt: P48431
• Host: Rabbit
• Immunogen: Amino acids 176-305 were used as the immunogen for the recombinant SOX2 antibody.
• Clonality: Monoclonal
• Isotype: IgG κ
• Type: Recombinant
• Applications: WB, IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Store the recombinant SOX2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This recombinant SOX2 antibody is available for research use only.