Nucleophosmin Antibody / NPM1
CAT:
800-V7607SAF-100UG
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Nucleophosmin Antibody / NPM1
- Description: The protein encoded by the NPM1 gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. [RefSeq]
- CAS Number: 9007-83-4
- UniProt: P06748
- Host: Mouse
- Immunogen: A portion of amino acids 185-287 from the human protein was used as the immunogen for the NPM antibody.
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Applications: IHC-P, WB
- Format: Purified
- Buffer: 1 mg/ml in 1X PBS; BSA free, sodium azide free
- Reconstitution: Store the NPM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
- Limitations: This NPM antibody is available for research use only.