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Recombinant ICAM3 Antibody

CAT: 0800-V7507-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V7507-100UGSize:100 µg
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Description
Recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.
CAS Number
9000-83-3
Specifications
Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (order BSA/sodium azide-free format), Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P32942
Host
Rabbit
Reactivity
Human
Immunogen
Full length recombinant human protein was used as the immunogen for the recombinant ICAM3 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
ICAM3/2873R
Type
Recombinant
Applications
Blocking, IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the recombinant ICAM3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant ICAM3 antibody is available for research use only.
Storage Conditions
Store the recombinant ICAM3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Membrane, cytoplasm
Image Legend
IHC staining of FFPE human tonsil tissue with recombinant ICAM3 antibody (clone ICAM3/2873R) . HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.

UniProtKB · P32942

Intercellular adhesion molecule 3

ICAM3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P32942
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ICAM3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ICAM-3
EC number
—
Processing
Precursor
Secondary accessions
Q6PD68
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Cell adhesionPhagocytosis

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

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