Recombinant Mammaglobin Antibody / SCGB2A2

• Description:

  Mammaglobin, also called Secretoglobin family 2A member 2, or SCGB2A2, is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues. Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.

• Specifications:

  Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 0.1-0.2 µg/mL for 30 min at RT, Immunofluorescence: 1-2 µg/mL

• UniProt:

  Q13296

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Full length recombinant human protein was used as the immunogen for the recombinant Mammaglobin antibody.

• Clonality:

  Recombinant Monoclonal

• Isotype:

  IgG κ

• Clone:

  MGB/2682R

• Type:

  Recombinant

• Applications:

  WB, IHC-P, IF

• Purity:

  Protein A affinity chromatography

• Format:

  Purified

• Buffer:

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

• Reconstitution:

  Store the recombinant Mammaglobin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This recombinant Mammaglobin antibody is available for research use only.

• Storage Conditions:

  Store the recombinant Mammaglobin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation:

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

• CAS Number:

  9000-83-3

• Location:

  Cytoplasmic, cell surface, nuclear

• Image Legend:

  IHC testing of FFPE human breast carcinoma stained with recombinant Mammaglobin antibody (clone MGB/2682R) . Required HIER: boiling tissue sections in 10mM citrate buffer, pH6, for 10-20 min followed by cooling at RT for 20 min.