SPTA1 Recombinant Antibody / Spectrin alpha 1

SPTA1 Recombinant Antibody / Spectrin alpha 1

• Description: This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3. [RefSeq]
• CAS Number: 9000-83-3
• UniProt: P02549
• Host: Mouse
• Immunogen: A portion of amino acids 356-475 from the human protein was used as the immunogen for the recombinant SPTA1 antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Type: Recombinant
• Applications: IHC-P
• Format: Purified
• Buffer: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
• Reconstitution: Store the recombinant SPTA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This recombinant SPTA1 antibody is available for research use only.