Products for Research Use Only
RegisterLogin

DC-SIGN Antibody / CD209

CAT: 0800-V7418IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V7418IHC-7MLSize:7 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
CAS Number
9000-83-3
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
Q9NNX6
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the DC-SIGN antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
C209/2749R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the DC-SIGN antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This DC-SIGN antibody is available for research use only.
Storage Conditions
Store the DC-SIGN antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Plasma membrane, secreted
Image Legend
IHC staining of FFPE human small intestine with recombinant DC-SIGN antibody (clone C209/2749R) . HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.

UniProtKB · Q9NNX6

CD209 antigen

CD209_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NNX6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD209
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8KAM4, A8MVQ9, G5E9C4, Q2TB19, Q96QP7, Q96QP8, Q96QP9, Q96QQ0, Q96QQ1, Q96QQ2, Q96QQ3, Q96QQ4, Q96QQ5, Q96QQ6, Q96QQ7, Q96QQ8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityCell adhesionEndocytosisHost-virus interactionImmunityInnate immunity

Coding sequence diversity

Alternative splicing

Ligand

CalciumLectinMannose-bindingMetal-binding

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoprotein

Molecular function

Host cell receptor for virus entryReceptor

Domain

RepeatSignal-anchorTransmembraneTransmembrane helix
Product Datasheet
Loading...

Related Products

CatalogName
V9406SAF-100UGCD209 Antibody / DC-SIGN
V9406-100UGCD209 Antibody / DC-SIGN
V9406-20UGCD209 Antibody / DC-SIGN
V7840-100UGRecombinant CD209 Antibody / DC-SIGN
V7840SAF-100UGRecombinant CD209 Antibody / DC-SIGN
V7840-20UGRecombinant CD209 Antibody / DC-SIGN
N1090-100UGDC-SIGN Antibody
R34899-100UGDC-SIGN Antibody
N1090-25UGDC-SIGN Antibody
RQ4373CD200 Antibody

Alternative Products

CatalogName
E021600CD209 (DC-SIGN) Antibody
GTR18205199-01CD209 / DC-SIGN Antibody
79-703CD209 (DC SIGN) Antibody
GTR17696141DC-SIGN/CD209 Antibody
43-700DC-SIGN / CD209 Antibody
GTR18574525DC-SIGN Antibody / CD209
GTR18225328CD209/DC-SIGN Antibody
A01025-1Anti-CD209/Dc Sign Antibody
35-1770-50Polyclonal Antibody to CD209 (DC-SIGN)
bsm-61560R-01CD209/DC-SIGN Recombinant Antibody

Popular Products