AKR1B1 Antibody / Aldose reductase

• Description:

  AKR1B1, also deisgnated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.

• UniProt:

  P15121

• Host:

  Mouse

• Immunogen:

  Recombinant protein was used as the immunogen for this Aldose reductase antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Applications:

  WB, IF, IHC-P

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Store the Aldose reductase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This Aldose reductase antibody is available for research use only.

• CAS Number:

  9007-83-4