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Recombinant CD6 Antibody

CAT: 0800-V7379SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V7379SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular 'scavenger receptor cysteine-rich' (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
CAS Number
9000-83-3
Specifications
Flow cytometry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P30203
Host
Rabbit
Reactivity
Human
Immunogen
Human recombinant protein was used as the immunogen for this recombinant CD6 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
C6/2884R
Type
Recombinant
Applications
FACS, IF, IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the recombinant CD6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant CD6 antibody is available for research use only.
Storage Conditions
Store the recombinant CD6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cell surface and Cytoplasmic
Image Legend
IHC staining of FFPE human tonsil tissue with recombinant CD6 antibody (clone C6/2884R) . HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
Product Datasheet
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