RPSA Antibody / 40S Ribosomal protein SA

RPSA Antibody / 40S Ribosomal protein SA

• Description: Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.
• CAS Number: 9007-83-4
• UniProt: P08865
• Host: Mouse
• Immunogen: Recombinant full length protein was used as the immunogen for the RPSA antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Applications: FACS, IF, WB, IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Reconstitution: Store the RPSA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This RPSA antibody is available for research use only.