Products for Research Use Only
RegisterLogin

CD63 Antibody / LAMP-3

CAT: 0800-V7190IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V7190IHC-7MLSize:7 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD63 functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. [UniProt]
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P08962
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human full-length protein was used as the immunogen for the CD63 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
CDLA63-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the CD63 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD63 antibody is available for research use only.
Storage Conditions
Store the CD63 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic
Image Legend
IHC testing of FFPE human prostate carcinoma with CD63 antibody (clone CDLA63-1) . HIER: FFPE testing requires sections to be boiled in pH6 10mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.

UniProtKB · P08962

CD63 antigen

CD63_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08962
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD63
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
F8VZE2, Q5TZP3, Q8N6Z9, Q9UCG6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndosomeLysosomeMembraneSecreted

PTM

GlycoproteinLipoproteinPalmitate

Biological process

Protein transportTransport

Domain

TransmembraneTransmembrane helix

Related Products

CatalogName
V3028-100UGLAMP-3 Antibody / CD63
V3028-20UGLAMP-3 Antibody / CD63
V3029SAF-100UGLAMP-3 Antibody / CD63
V3028SAF-100UGLAMP-3 Antibody / CD63
V3029IHC-7MLLAMP-3 Antibody / CD63
V3029-100UGLAMP-3 Antibody / CD63
V3029-20UGLAMP-3 Antibody / CD63
V5450SAF-100UGRecombinant LAMP-3 Antibody / CD63
V4299-100UGRecombinant LAMP-3 Antibody / CD63
V5450-100UGRecombinant LAMP-3 Antibody / CD63

Alternative Products

CatalogName
GTR18574193CD63 Antibody / LAMP-3
GTR18572937LAMP-3 Antibody / CD63

Popular Products