DsDNA Antibody

• Description:

  Deoxyribonucleic acid (DNA) is a nucleic acid that stores long-term information regarding the development and function of all known living organisms. DNA consists of two long nucleotide polymers, which are composed of four bases, namely adenine, thymine, guanine and cytosine, all of which are flanked by a phosphate-deoxyribose backbone. This mAb can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells.

• Specifications:

  Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT (1)

• UniProt:

  Not Known

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Cell nuclei were used as the immunogen for the dsDNA antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG3 κ

• Clone:

  DRNC1-1

• Applications:

  IHC-P

• Purity:

  Protein G affinity chromatography

• Format:

  Purified

• Buffer:

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

• Reconstitution:

  Store the dsDNA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This dsDNA antibody is available for research use only.

• Storage Conditions:

  Store the dsDNA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation:

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

• CAS Number:

  9007-83-4

• Location:

  Nuclear

• Image Legend:

  IHC testing of FFPE human tonsil with dsDNA antibody (clone DRNC1-1) . FFPE testing requires sections to be boiled in pH 9 10mM Tris with 1mM EDTA for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.