CA9 Antibody / Carbonic Anhydrase IX

CA9 Antibody / Carbonic Anhydrase IX

• Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. Carbonic anhydrase IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. [RefSeq]
• CAS Number: 9007-83-4
• UniProt: Q16790
• Host: Mouse
• Immunogen: Recombinant human protein was used as the immunogen for the CAIX antibody.
• Clonality: Monoclonal
• Isotype: IgG2b κ
• Applications: WB, IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Reconstitution: Store the CAIX antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This CAIX antibody is available for research use only.