CA3 Antibody / Carbonic Anhydrase III

CA3 Antibody / Carbonic Anhydrase III

• Description: Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA III (carbonic anhydrase III), also known as Car3 or CA3, is a 260 amino acid cytoplasmic protein that is specifically expressed in muscle. Belonging to the a-carbonic anhydrase family, CA III is activated by proton donors such as imidazole and dipeptide histidylhistidine, and is inhibited by coumarins and sulfonamide derivatives such as acetazolamide.
• CAS Number: 9007-83-4
• UniProt: P07451
• Host: Mouse
• Immunogen: A recombinant fragment of human CA3 protein was used as the immunogen for the Carbonic Anhydrase 3 antibody.
• Clonality: Monoclonal
• Isotype: IgG2a κ
• Applications: IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Aliquot the Carbonic Anhydrase 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This Carbonic Anhydrase 3 antibody is available for research use only.