CD59 Antibody

CAT: 0800-V7168IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
CAT#:0800-V7168IHC-7MLSize:7 mL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. [UniProt]
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P13987
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the CD59 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CDLA59-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the CD59 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD59 antibody is available for research use only.
Storage Conditions
Store the CD59 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Plasma membrane, cytoplasm
Image Legend
IHC testing of FFPE human tongue with CD59 antibody (clone CDLA59-1) .

Related Products

CatalogName
V9218-100UGCD5 Ligand Antibody / CD5L
V9218SAF-100UGCD5 Ligand Antibody / CD5L
V9218-20UGCD5 Ligand Antibody / CD5L
V4191SAF-100UGCD56 Antibody
V8777SAF-100UGCD55 Antibody
V7310-20UGCD56 Antibody
V7310IHC-7MLCD56 Antibody
V2530IHC-7MLCD57 Antibody
V8377-20UGCD5L Antibody
V2535-100UGCD57 Antibody

Alternative Products

CatalogName
abx270064-01CD59 Glycoprotein (CD59) Antibody

Popular Products