Products for Research Use Only

SHBG Antibody

CAT: 0800-V7152IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
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CAT#:0800-V7152IHC-7MLSize:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sex Hormone Binding Globulin, also called Androgen Binding Protein (ABP) and Testosterone-Estradiol-Binding Globulin (TEBG), functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. [UniProt]
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P04278
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the SHBG antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
TTEB3
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the SHBG antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This SHBG antibody is available for research use only.
Storage Conditions
Store the SHBG antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic & extracellular (secreted)
Image Legend
IHC testing of FFPE human testicular carcinoma with SHBG antibody (clone TTEB3) . Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.

UniProtKB · P04278

Sex hormone-binding globulin

SHBG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04278
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SHBG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SHBG
EC number
—
Processing
Precursor
Secondary accessions
B0FWH4, B4DYU0, E9PGW1, F5H5Z8, I3L1N7, P14689, Q16616, Q3MIL0, Q6ISD2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoprotein

Ligand

Lipid-bindingSteroid-binding

Domain

RepeatSignal

Cellular component

Secreted
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