Products for Research Use Only
RegisterLogin

MITF Antibody

CAT: 0800-V7109IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V7109IHC-7MLSize:7 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MITF (microphthalmia transcription factor) is a transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR) . Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1) . Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. [UniProt]
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
O75030
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the MITF antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
MPAF3
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the MITF antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This MITF antibody is available for research use only.
Storage Conditions
Store the MITF antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Nuclear
Image Legend
IHC testing of FFPE human melanoma with MITF antibody (clone MPAF3) . Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min. followed by cooling at RT for 20 min.

Related Products

CatalogName
V5098-20UGSTING Antibody / MITA / ERIS / TMEM17
V5093-100UGSTING1 Antibody / ERIS / MITA / TMEM17
V5092-100UGSTING1 Antibody / MITA / ERIS / TMEM173
V5097-100UGSTING1 Antibody / TMEM173 / MITA / ERIS
V5097SAF-100UGSTING1 Antibody / TMEM173 / MITA / ERIS
V5099-20UGSTING1 Antibody / ERIS / MITA / TMEM17
V5099SAF-100UGSTING1 Antibody / ERIS / MITA / TMEM17
V5092SAF-100UGSTING1 Antibody / MITA / ERIS / TMEM173
V5098SAF-100UGSTING Antibody / MITA / ERIS / TMEM17
V5092-20UGSTING1 Antibody / MITA / ERIS / TMEM173

Alternative Products

CatalogName
GWB-36C5ADMITF, Antibody
AF7641-01MITF Antibody

Popular Products