MITF Antibody
CAT:
800-V7109-100UG
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MITF Antibody
- Description: MITF (microphthalmia transcription factor) is a transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. [UniProt]
- CAS Number: 9007-83-4
- UniProt: O75030
- Host: Mouse
- Immunogen: Recombinant full-length human protein was used as the immunogen for the MITF antibody.
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Applications: IHC-P
- Format: Purified
- Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
- Reconstitution: Store the MITF antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
- Limitations: This MITF antibody is available for research use only.