Androgen Receptor Antibody

Androgen Receptor Antibody

• Description: The Androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. [RefSeq]
• CAS Number: 9007-83-4
• UniProt: P10275
• Host: Mouse
• Immunogen: Recombinant full-length human AR protein was used as the immunogen for the Androgen Receptor antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Applications: IHC-P
• Format: Purified
• Buffer: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
• Reconstitution: Store the Androgen Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This Androgen Receptor antibody is available for research use only.