GFAP Antibody

• Description :

  Glial fibrillary acidic protein is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [RefSeq]

• Specifications :

  The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  Native Glial fibrillary acidic protein was used as the immunogen for this GFAP antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG1 k

• Clone :

  GFA12-3

• Applications :

  IHC-P

• Purity :

  Protein G affinity chromatography

• Format :

  Purified

• Buffer :

  Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

• Reconstitution :

  Store the GFAP antibody at 2-8oC.

• Limitations :

  This GFAP antibody is available for research use only.

• Storage Conditions :

  Store the GFAP antibody at 2-8°C.

• Formulation :

  Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

• CAS Number :

  9007-83-4

• Location :

  Cytoplasmic

• Image Legend :

  IHC testing of FFPE human brain and GFAP antibody (clone GFA12-3) . FFPE testing requires sections to be boiled in pH 9 10mM Tris with 1mM EDTA for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.