CD79b Antibody

CAT: 0800-V3810SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V3810SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. [UniProt]
CAS Number
9007-83-4
Specifications
IHC (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P40259
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 29-159 was used as the immunogen for the CD79b antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
CDLA79b-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the CD79b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD79b antibody is available for research use only.
Storage Conditions
Store the CD79b antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
The stated application concentrations are suggested starting points. Titration of the CD79b antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cell surface
Image Legend
IHC testing of FFPE human tonsil tissue with CD79b antibody (clone CDLA79b-1) . HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.

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