Cefquinome

• Description:

  Cefquinome is a broad-spectrum cephem antibiotic that has inhibitory effects on a variety of Gram-positive and Gram-negative bacteria, including Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae[1][2][3].

• UNSPSC:

  12352005

• Hazard Statement:

  H317-H334

• Target:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/cefquinome.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1[C@@H] (NC (/C (C2=CSC (N) =N2) =N\OC) =O) [C@@]3 ([H]) SCC (C[N+]4=C5CCCCC5=CC=C4) =C (C ([O-]) =O) N13

• Molecular Formula:

  C23H24N6O5S2

• Molecular Weight:

  528.60

• Precautions:

  P261-P272-P280-P284-P302+P352-P304+P340-P362+P364-P501

• References & Citations:

  [1]Chin NX, et al. In vitro activity of cefquinome, a new cephalosporin, compared with other cephalosporin antibiotics. Diagn Microbiol Infect Dis. 1992 May-Jun;15 (4) :331-7.|[2]Qu S, et al., Cefquinome-loaded microsphere formulations against Klebsiella pneumonia infection during experimental infections. Drug Deliv. 2018 Nov;25 (1) :909-915.|[3]Limbert M, et al., Antibacterial activities in vitro and in vivo and pharmacokinetics of cefquinome (HR 111V), a new broad-spectrum cephalosporin. Antimicrob Agents Chemother. 1991 Jan;35 (1) :14-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  84957-30-2