Phleomycin

• UNSPSC Description:

  Phleomycin is an anticancer glycopeptide antibiotic found in Streptomyces verticillus, which cause DNA cleavage. Phleomycin binds and intercalates DNA to damage the integrity of the double helix, which is similar to Bleomycin (HY-17565A)[1].

• Target Antigen:

  Antibiotic; Bacterial; DNA/RNA Synthesis

• Type:

  Natural Products

• Related Pathways:

  Anti-infection;Cell Cycle/DNA Damage

• Field of Research:

  Cancer; Infection

• Assay Protocol:

  https://www.medchemexpress.com/phleomycin.html

• Purity:

  95.0

• Solubility:

  H2O : 100 mg/mL (ultrasonic)

• Smiles:

  [Phleomycin]

• References & Citations:

  [1] Kamila Stokowa-Sołtys, et al. Phleomycin complex - Coordination mode and in vitro cleavage of DNA. J Inorg Biochem. 2019 Jun;195:71-82.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, stored under nitrogen)

• Clinical Information:

  No Development Reported

• CAS Number:

  11006-33-0