MUC6 Recombinant Antibody / Gastric Mucin

• Description:

  MUC6 or gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

• UniProt:

  Q6W4X9

• Host:

  Rabbit

• Immunogen:

  A peptide from the Mucin-6 tandem repeat sequence was used as the immunogen for the recombinant MUC6 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG κ

• Type:

  Recombinant

• Applications:

  IHC-P

• Format:

  Purified

• Buffer:

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

• Reconstitution:

  Store the recombinant MUC6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This recombinant MUC6 antibody is available for research use only.

• CAS Number:

  9000-83-3