NKX2.2 Recombinant Antibody

NKX2.2 Recombinant Antibody

• Description: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
• CAS Number: 9000-83-3
• UniProt: O95096
• Host: Mouse
• Immunogen: Human recombinant protein was used as the immunogen for this recombinant NKX2.2 antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Type: Recombinant
• Applications: IHC-P
• Format: Purified
• Buffer: 1 mg/ml in 1X PBS; BSA free, sodium azide free
• Reconstitution: Store the recombinant NKX2.2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This recombinant NKX2.2 antibody is available for research use only.