Human IgG4 Recombinant Antibody

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Human IgG4 Recombinant Antibody

CAT:

800-V3574IHC-7ML

Size:

7 mL

Price:

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Human IgG4 Recombinant Antibody

Description: The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Reportedly, a large population of patients with recurrent respiratory tract infection has low IgG4 concentrations. IgG4-related sclerosing disease has been recognized as a systemic disease entity characterized by an elevated serum IgG4 level, sclerosing fibrosis, and diffuse lymphoplasmacytic infiltration with the presence of many IgG4-positive plasma cells. IgG4 is overexpressed in inflammatory pseudotumor (IPT) and under expressed in inflammatory myofibroblastic tumor (IMT). In pulmonary nodular lymphoid hyperplasia (PNLH), there are an increased number of IgG4+ plasma cells.
UniProt: P01861
Host: Mouse
Immunogen: A human recombinant protein corresponding to the Fc region was used as the immunogen for this recombinant IgG4 antibody.
Clonality: Monoclonal
Isotype: IgG1 κ
Type: Recombinant
Applications: IHC-P
Format: Purified
Buffer: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution: Store the recombinant IgG4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations: This recombinant IgG4 antibody is available for research use only.

Complementary Product Range

Our range of products, including Human IgG4 Recombinant Antibody, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

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Cat	Name
RQ4982	Human IgG4 Recombinant Antibody
V3695-20UG	Human IgG4 Recombinant Antibody
V3574-100UG	Human IgG4 Recombinant Antibody
V3574IHC-7ML	Human IgG4 Recombinant Antibody
V3574SAF-100UG	Human IgG4 Recombinant Antibody
V3695-100UG	Human IgG4 Recombinant Antibody
V3574-20UG	Human IgG4 Recombinant Antibody
V3695SAF-100UG	Human IgG4 Recombinant Antibody
V3454-20UG	Human IgG4 Antibody
V3454-100UG	Human IgG4 Antibody