Products for Research Use Only
RegisterLogin

Bcl6 Antibody

CAT: 0800-V3457-20UGSize: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V3457-20UGSize:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Antibody to Bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show Bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, Bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) . The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large (L&H) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P41182
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 256-389 from the human protein were used as the immunogen for the Bcl6 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
BCL6/1526
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Bcl6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Bcl6 antibody is available for research use only.
Storage Conditions
Store the Bcl6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Bcl6 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC testing of FFPE human tonsil tissue with Bcl6 antibody (clone BCL6/1526) . Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.

Related Products

CatalogName
V5023SAF-100UGB-Cell Lymphoma 6 Antibody / BCL6
V5023-100UGB-Cell Lymphoma 6 Antibody / BCL6
V5023-20UGB-Cell Lymphoma 6 Antibody / BCL6
V7145-100UGBcl2 Antibody
RQ5324BCL2 Antibody
V7145IHC-7MLBcl2 Antibody
RQ6314BCL3 Antibody
V2833-100UGBcl2 Antibody
V7145-20UGBcl2 Antibody
V7145SAF-100UGBcl2 Antibody

Alternative Products

CatalogName
33-840Bcl6 Antibody [BCL6/1527]
33-839Bcl6 Antibody [BCL6/1475]
33-802Bcl6 Antibody [BCL6/1526]
70R-11805BCL6 antibody

Popular Products